Kingdom :
Plantae
Subkingdom :
Tracheobionta
Superdivisi :
Spermatophyta
Division :
Magnoliophyta
Class :
Plant Taxonomy
Subclass
Magnoliidae
Order :
Piperales
Family :
Piperaceae
Genus :
Piper
Species :
Piper aduncum l.
Synonym
Piper
angustifolium
Piper
celtidifolium
Piper
elongatum
Piper
aduncum Grow :
natural forest, plantation acreage.
Piper
aduncum Stem :
Woody, ovoid, pointed tip, base rounded, flat edges on each book, fluffy stalk
is cylindrical, 5-10 mm long, the leaves are 10-14 cm, width 5-6 cm, light green.
Piper
aduncum Flowers :
compounds, form a, have sex one or two patron leaves, stemmed from 0.5 to 1.25
mm, curved, stalk short stamens, head of a small juice, fruit would sit, stigma
two to three, short, white, yellowish white.
Piper
aduncum Fruit :
short-stemmed, long ears of 12-14 cm long, greenish-yellow, still young after
the old green. Beans: small, Brown. Roots: riding, brownish white.
Piper
aduncum Root :
the root is white and Brown single.
Piper
aduncum leaves contain saponins, polyphenols, flavonoida, essential oil,
dihydrochalcone, piperaduncin A, B, and C, as well as 6 ° 2′-dihidroksi-4
°-metoksidihidrokhalkon (DMC) and 6 ° 2′,
4-4-trihidroksi;-metoksidihidrokhalkon (asebogenin).
Chalcone
and its derivation is a group of compounds is reported as showing a promising
anticancer activity. It is the precursor compounds of flavonoids and
isoflavonoid abundant on food crops. Previous research suggests that its
derivation and Chalcone have anticancer activity in some cancer cells. Natural
and synthetic Chalcone shows effects of effecttumor cells in ovarian cancer
cells and cancer cells gastrik HGC-27.
Hydroxyl Chalcone isoliquiritigenin and
shows a strong inhibitor on Carcinogenesis of the skin. Some research suggests
that Chalcone also as kemoprevensi agent, capable of inhibiting Carcinogenesis
induced by chemical agents through increased levels of glutation reduced.
However, the actual mechanism of Chalcone compounds on tumor cells still
continues to unfold. It has been suggested that inhibits cell proliferation of
isoliquiritigenin lung cancer A549 cell cycle with stop in G2/M and induces
expression of p21 protein.
Research on hepatocellular carcinoma HepG2 cells
showed that the function of Chalcone and its derivation through inhibition of
the activity of tyrosine kinase receptors Epidermal Growth Factor. Mode of
action the Chalcone hydroxyl also proposed, based on studies in rat
hepatocytes, induction through the formation of prooksidan radicals.
Piper
aduncum trunk SAP is effective as a cure boils and
new
cuts recently. To cure boils, used Piper aduncum stem SAP ± 2
ml,
then smeared on ulcers.